Defining the HIV Capsid Binding Site of Nucleoporin 153

ABSTRACT The interaction between the HIV-1 capsid and human nucleoporin 153 (NUP153) is vital for delivering the HIV-1 preintegration complex into the nucleus via the nuclear pore complex. The interaction with the capsid requires a phenylalanine/glycine-containing motif in the C-terminus of NUP153 (...

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Principais autores:	Shunji Li, Jagdish Suresh Patel, Jordan Yang, Angela Marie Crabtree, Brenda Marilyn Rubenstein, Peik Karl Lund-Andersen, Frederick Marty Ytreberg, Paul Andrew Rowley
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology 2022-10-01
叢編:	mSphere
主題:	HIV NUP153 capsid molecular modeling FoldX PyRosetta
在線閱讀:	https://journals.asm.org/doi/10.1128/msphere.00310-22
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