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Mimotope-based vaccines of Leishmania infantum antigens and their protective efficacy against visceral leishmaniasis.

BACKGROUND: The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display technology to identify new immunogens, which were evaluated as vaccines in the murine model of visceral leishmaniasis (VL). Epitope-...

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Hlavní autoři: Lourena Emanuele Costa, Luiz Ricardo Goulart, Nathália Cristina de Jesus Pereira, Mayara Ingrid Sousa Lima, Mariana Costa Duarte, Vivian Tamietti Martins, Paula Sousa Lage, Daniel Menezes-Souza, Tatiana Gomes Ribeiro, Maria Norma Melo, Ana Paula Fernandes, Manuel Soto, Carlos Alberto Pereira Tavares, Miguel Angel Chávez-Fumagalli, Eduardo Antonio Ferraz Coelho
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4198211?pdf=render
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