Australian Aboriginal Otitis-Prone Children Produce High-Quality Serum IgG to Putative Nontypeable Haemophilus influenzae Vaccine Antigens at Lower Titres Compared to Non-Aboriginal Children

BackgroundNontypeable Haemophilus influenzae (NTHi) is the most common bacterial otopathogen associated with otitis media (OM). NTHi persists in biofilms within the middle ears of children with chronic and recurrent OM. Australian Aboriginal children suffer exceptionally high rates of chronic and re...

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Autori principali:	Sharon L. Clark, Elke J. Seppanen, Lea-Ann S. Kirkham, Laura A. Novotny, Lauren O. Bakaletz, Allan W. Cripps, Karli Corscadden, Harvey Coates, Shyan Vijayasekaran, Peter C. Richmond, Ruth B. Thornton
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-04-01
Serie:	Frontiers in Cellular and Infection Microbiology
Soggetti:	otitis media Australian Aboriginal children IgG nontypeable Haemophilus influenzae avidity immunology
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.767083/full
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