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Metabolic benefits of methionine restriction in adult mice do not require functional methionine sulfoxide reductase A (MsrA)

Abstract Methionine restriction (MR) extends lifespan and improves several markers of health in rodents. However, the proximate mechanisms of MR on these physiological benefits have not been fully elucidated. The essential amino acid methionine plays numerous biological roles and limiting its availa...

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Autori principali: Kevin M. Thyne, Adam B. Salmon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2022-03-01
Serie:Scientific Reports
Accesso online:https://doi.org/10.1038/s41598-022-08978-4
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