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A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development.

Plasmodium sporozoites invade host hepatocytes and develop as liver stages (LS) before the onset of erythrocytic infection and malaria symptoms. LS are clinically silent, and constitute ideal targets for causal prophylactic drugs and vaccines. The molecular and cellular mechanisms underlying LS deve...

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Bibliografische gegevens
Hoofdauteurs: Olivier Silvie, Kristin Goetz, Kai Matuschewski
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2008-06-01
Reeks:PLoS Pathogens
Online toegang:http://europepmc.org/articles/PMC2398788?pdf=render
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