FK506 biosynthesis is regulated by two positive regulatory elements in <it>Streptomyces tsukubaensis</it>

<p>Abstract</p> <p>Background</p> <p>FK506 (Tacrolimus) is an important immunosuppressant, produced by industrial biosynthetic processes using various <it>Streptomyces</it> species. Considering the complex structure of FK506, it is reasonable to expect complex regulatory networks controlling its bio...

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Autori principali:	Goranovič Dušan, Blažič Marko, Magdevska Vasilka, Horvat Jaka, Kuščer Enej, Polak Tomaž, Santos-Aberturas Javier, Martínez-Castro Miriam, Barreiro Carlos, Mrak Peter, Kopitar Gregor, Kosec Gregor, Fujs Štefan, Martín Juan F, Petković Hrvoje
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2012-10-01
Serie:	BMC Microbiology
Soggetti:	FK506 Tacrolimus <it>Streptomyces tsukubaensis</it> Biosynthesis Transcriptional regulator
Accesso online:	http://www.biomedcentral.com/1471-2180/12/238
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