Aiming the magic bullet: targeted delivery of imaging and therapeutic agents to solid tumors by pHLIP peptides

The family of pH (Low) Insertion Peptides (pHLIP) comprises a tumor-agnostic technology that uses the low pH (or high acidity) at the surfaces of cells within the tumor microenvironment (TME) as a targeted biomarker. pHLIPs can be used for extracellular and intracellular delivery of a variety of ima...

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Bibliographic Details

Main Authors:	Yana K. Reshetnyak, Oleg A. Andreev, Donald M. Engelman
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2024-03-01
Series:	Frontiers in Pharmacology
Subjects:	pHLIP targeting of cell acidity cell acidity as a biomarker targeting diverse tumor cells immune therapy strategies targeted nanoparticle delivery tumor imaging and diagnosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1355893/full
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