A Shigella flexneri 2a synthetic glycan-based vaccine induces a long-lasting immune response in adults

Abstract Shigella is a leading cause of moderate to severe diarrhea worldwide and of diarrhea-associated deaths in children under 5 years of age in low-and middle-income countries. A vaccine against shigellosis is in high demand. SF2a-TT15, a synthetic carbohydrate-based conjugate vaccine candidate...

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Hlavní autoři:	Shiri Meron-Sudai, Valeria Asato, Amos Adler, Anya Bialik, Sophy Goren, Ortal Ariel-Cohen, Arava Reizis, Laurence A. Mulard, Armelle Phalipon, Dani Cohen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2023-03-01
Edice:	npj Vaccines
On-line přístup:	https://doi.org/10.1038/s41541-023-00624-y
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