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STX4 Is Indispensable for Mitochondrial Homeostasis in Skeletal Muscle

ABSTRACT Background Mitochondrial homeostasis is vital for optimal skeletal muscle integrity. Mitochondrial quality control (MQC) mechanisms that are essential for maintaining proper functions of mitochondria include mitochondrial biogenesis, dynamics and mitophagy. Previously, Syntaxin 4 (STX4), tr...

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Principais autores: Joseph M. Hoolachan, Rekha Balakrishnan, Erika M. McCown, Karla E. Merz, Chunxue Zhou, Elizabeth Bloom‐Saldana, Patrick T. Fueger, Angelica Hamilton, Tali Kiperman, Ke Ma, Eunjin Oh, Lei Jiang, Patrick Pirrotte, Orian Shirihai, Debbie C. Thurmond
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-12-01
Serier:Journal of Cachexia, Sarcopenia and Muscle
Fag:
mitochondria
muscle
quality control
STX4
Online adgang:https://doi.org/10.1002/jcsm.70113
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