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Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3

Abstract The t(14;19)(q32;q13) is a rare recurring translocation found in B-cell lymphoproliferative malignancies, involving the Bcl-3 gene. This chromosomal translocation is often found in patients under the age of 50 and causes a more progressive disease. The Bcl-3 gene encodes a protein belonging...

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Autori principali: Renée Daams, Thi Thu Phuong Tran, Mohamed Jemaà, Wondossen Sime, Ruta Mickeviciute, Sara Ek, Lars Rönnstrand, Julhash U. Kazi, Ramin Massoumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2024-09-01
Serie:Cell Death and Disease
Accesso online:https://doi.org/10.1038/s41419-024-07067-w
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