Targeted Therapy With PI3K and FGFR Inhibitors on Human Papillomavirus Positive and Negative Tonsillar and Base of Tongue Cancer Lines With and Without Corresponding Mutations

ObjectivesHuman papillomavirus positive (HPV+) tonsillar and base of tongue squamous cell carcinoma (TSCC/BOTSCC), the major subsites of oropharyngeal squamous cell carcinoma (OPSCC) have favorable outcome, but upon relapse, outcome is poor and new therapies needed. Since, phosphatidyl-inositol-4,5-...

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Auteurs principaux:	Stefan Holzhauser, Nicole Wild, Mark Zupancic, Ramona G. Ursu, Cinzia Bersani, Anders Näsman, Ourania N. Kostopoulou, Tina Dalianis
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2021-05-01
Collection:	Frontiers in Oncology
Sujets:	head neck cancer HPV tonsillar cancer base of tongue cancer oropharyngeal cancer FGFR
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fonc.2021.640490/full
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