TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy
Abstract Background Studies have shown that tet methylcytosine dioxygenase 2 (TET2) is highly expressed in diabetic retinopathy (DR), which reduces the DNA methylation of downstream gene promoters and activates the transcription. Abnormally expressed TET2 and downstream genes in a high-glucose envir...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-01-01
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| Colecção: | Clinical Epigenetics |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s13148-023-01619-1 |
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