Lipidated DAPEG Polymers as a Non-Toxic Transfection Agent—Influence of Fatty Acid Side Chain on Transfection Efficacy

This study describes the synthesis, interaction with DNA, and transfection efficacy of eight lipidated compounds based on a recently published non-lipidated parent molecule, an octamer of 2,3-<span style="font-variant: small-caps;">l</span>-Dap, carrying the guanidine group on...

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Main Authors: Wiktoria Mallek, Anita Romanowska, Wiktoria Machowicz, Agnieszka Piwkowska, Adam Lesner, Magdalena Wysocka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-04-01
Colecção:Molecules
Assuntos:
peptidomimetics
transfection
lipidated polymers
Acesso em linha:https://www.mdpi.com/1420-3049/30/7/1644
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