Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

Non‐small cell lung cancer (NSCLC) affects 10–50% of patients with epidermal growth factor receptor (EGFR) mutations. Osimertinib is a third‐generation EGFR tyrosine kinase inhibitor (TKI) that radically changes the outcome of patients with tumors bearing EGFR sensitizing or EGFR T790M resistance mu...

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Hauptverfasser:	David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2025-05-01
Schriftenreihe:	FEBS Open Bio
Schlagworte:	chicken chorioallantoic membrane epidermal growth factor receptor non‐small cell lung cancer transcriptomics analysis
Online-Zugang:	https://doi.org/10.1002/2211-5463.13970
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