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Appraising the performance of genotyping tools in the prediction of coreceptor tropism in HIV-1 subtype C viruses

<p>Abstract</p> <p>Background</p> <p>In human immunodeficiency virus type 1 (HIV-1) infection, transmitted viruses generally use the CCR5 chemokine receptor as a coreceptor for host cell entry. In more than 50% of subtype B infections, a switch in coreceptor tropism from CCR5- to CXCR4-use occurs du...

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Enregistré dans:
Auteurs principaux: Crous Saleema, Shrestha Ram, Travers Simon A
Format: Artigo
Langue:Inglês
Publié: BMC 2012-09-01
Collection:BMC Infectious Diseases
Sujets:
Human immunodeficiency virus
Coreceptor
Chemokine receptors
CXCR4
CCR5
Genotype
Phenotype
Subtype C
Accès en ligne:http://www.biomedcentral.com/1471-2334/12/203
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