Bimetallic Iron–Palladium Catalyst System as a Lewis-Acid for the Synthesis of Novel Pharmacophores Based Indole Scaffold as Anticancer Agents

The Friedel–Crafts reaction between substituted indoles as nucleophiles with chalcones-based benzofuran and benzothiophene scaffolds was carried out by employing a highly efficient bimetallic iron–palladium catalyst system. This catalytic approach produced the desired <i>bis</i>-heteroaryl products...

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Principais autores:	Mohammad Shahidul Islam, M. Ali, Abdullah Mohammed Al-Majid, Abdullah Saleh Alamary, Saeed Alshahrani, Sammer Yousuf, Muhammad Iqbal Choudhary, Assem Barakat
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-04-01
Series:	Molecules
Assuntos:	Friedel–Crafts reaction Lewis acids indoles benzothiophene benzofuran anti-cancer activity
Acceso en liña:	https://www.mdpi.com/1420-3049/26/8/2212
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