Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that degrades mRNAs carrying a premature termination codon. Its inhibition, alone or in combination with other approaches, could be exploited to develop therapies for genetic diseases caused by a nonsense mutation. This, however, requ...
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| Автори: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
MDPI AG
2023-10-01
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| Серія: | Biomedicines |
| Предмети: | |
| Онлайн доступ: | https://www.mdpi.com/2227-9059/11/10/2801 |
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