Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota

IntroductionAlopecia areata (AA), an autoimmune hair-loss disease due to follicular inflammatory cell infiltration, lacks an ideal cure. The Periplaneta Americana (PA) extract (PA-011), a traditional Chinese medicine with anti-inflammatory, antioxidant, tissue-repair-promoting, and immune-regulating...

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Bibliografische Detailangaben

Hauptverfasser:	Tangfei Guan, Xin Yang, Canhui Hong, Jiali Zhu, Peiyun Xiao, Yongshou Yang, Chenggui Zhang, Zhengchun He
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-08-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	Alopecia areata Periplaneta americana (L.) extract network pharmacology transcriptomics metabolomics microbiomics
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1590648/full
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