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Optimization of Synthesis of the Amino Lipid ECO for Effective Delivery of Nucleic Acids

Nucleic acids are promising for a variety of therapies, such as cancer therapy and the gene therapy of genetic disorders. The therapeutic efficacy of nucleic acids is reliant on the ability of their efficient delivery to the cytosol of the target cells. Amino lipids have been developed to aid in the...

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Principais autores: Andrew L. Schilb, Josef H. Scheidt, Amita M. Vaidya, Zhanhu Sun, Da Sun, Sangjoon Lee, Zheng-Rong Lu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Pharmaceuticals
Fag:
gene therapy
ECO
miRNA
siRNA
plasmid
RNA interference
Online adgang:https://www.mdpi.com/1424-8247/14/10/1016
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