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Transcriptomic signatures of individual cell types in cerebral cavernous malformation

Abstract Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfunctional cellular crosstalk remains un...

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Kaydedildi:
Asıl Yazarlar: Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Je Yeong Sone, Thomas Moore, Dorothy DeBiasse, Agnieszka Stadnik, Justine J. Lee, Robert Shenkar, Janne Koskimäki, Miguel A. Lopez-Ramirez, Douglas A. Marchuk, Mark H. Ginsberg, Mark L. Kahn, Changbin Shi, Issam A. Awad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-01-01
Seri Bilgileri:Cell Communication and Signaling
Konular:
Cerebral cavernous malformation
VEGFA/VEGFR2
Transcriptome
Cell–cell interaction
Online Erişim:https://doi.org/10.1186/s12964-023-01301-2
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