Genome—annotated bivariate analysis of shared heritability in autoimmune hepatitis with psychiatric comorbidity

Abstract Studies indicate a high psychiatric burden in autoimmune hepatitis (AIH) patients, yet research on their genetic links remains unclear. This study comprehensively explores their genetic connections. The correlation metric, genetic correlation (rg), can measure the shared biological basis an...

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Bibliografische Detailangaben

Hauptverfasser:	Li Liu, Jing Chen, Tianxu Chen, Junlin Li, Qiong Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-12-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Autoimmune hepatitis Psychiatric disorders Pleiotropic loci Shared genetic architecture
Online-Zugang:	https://doi.org/10.1038/s41598-025-30962-x
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