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Lupeol Acetate and α-Amyrin Terpenes Activity against <i>Trypanosoma cruzi</i>: Insights into Toxicity and Potential Mechanisms of Action

Background: Chagas disease is a potentially fatal disease caused by the parasite <i>Trypanosoma cruzi</i>. There is growing scientific interest in finding new and better therapeutic alternatives for this disease’s treatment. Methods: A total of 81 terpene compounds with potential trypanocidal activi...

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Hoofdauteurs: Daniel Pardo-Rodriguez, Andres Cifuentes-López, Juan Bravo-Espejo, Ibeth Romero, Jorge Robles, Claudia Cuervo, Sol M. Mejía, Jair Tellez
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2023-05-01
Reeks:Tropical Medicine and Infectious Disease
Onderwerpen:
Chagas disease
terpenes trypanocidal effect
cysteine synthase
docking
molecular dynamics
<i>Trypanosoma cruzi</i>
Online toegang:https://www.mdpi.com/2414-6366/8/5/263
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