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Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development

Abstract Background Laminins are high-molecular weight (400 ~ 900 kDa) proteins in extracellular matrix, which serve as major component of the basal lamina, and play a crucial role in promoting tumor cell migration. This study aimed at characterizing the role of laminin in promoting cancer developme...

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Auteurs principaux: Nan Hao, Daming Yang, Tianpei Liu, Shucheng Liu, Xinsheng Lu, Libo Chen
Format: Artigo
Langue:Inglês
Publié: BMC 2022-05-01
Collection:BMC Cancer
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Accès en ligne:https://doi.org/10.1186/s12885-022-09645-7
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