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Membrane Lipids in the Thyroid Comparing to Those in Non-Endocrine Tissues Are Less Sensitive to Pro-Oxidative Effects of Fenton Reaction Substrates

Iron is an essential microelement for the proper functioning of many organs, among others it is required for thyroid hormone synthesis. However, its overload contributes to the increased formation of reactive oxygen species via Fenton chemistry (Fe2++H2O2→Fe3++˙OH + OH−), and it is potentially toxic...

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Principais autores: Jan Stępniak, Aleksandra Rynkowska, Małgorzata Karbownik-Lewińska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-06-01
coleção:Frontiers in Molecular Biosciences
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2022.901062/full
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