In vitro effects of tensile strain on cancer-associated and matched normal fibroblasts derived from oral squamous cell carcinoma: an exploratory study

Abstract Background Mechanical forces, particularly tensile stress, influence tumor progression by modulating cancer-associated fibroblast (CAF) behaviour and extracellular matrix remodelling, yet their role in oral cancer remains insufficiently defined. To our knowledge, this is the first study inv...

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Bibliografische gegevens

Hoofdauteurs:	Nadine Wiesmann-Imilowski, Sebahat Kaya, Andressa V. B. Nogueira, Victoria Langer, Stefanie Zimmer, Johannes Mockenhaupt, Johannes U. Mayer, James Deschner, Jürgen Brieger, Peer W. Kämmerer
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2026-07-01
Reeks:	BMC Cancer
Onderwerpen:	Oral Squamous Cell Carcinoma (OSCC) Cancer-associated Fibroblasts (CAFs) Tumor Microenvironment (TME) Mechanotransduction Tensile Stress Fibroblast Gap Closure
Online toegang:	https://doi.org/10.1186/s12885-026-16568-0
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