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The genetic and pharmacogenomic landscape of snoRNAs in human cancer

Abstract Emerging evidence has revealed significant roles for small nucleolar RNAs (snoRNAs) in tumorigenesis. However, the genetic and pharmacogenomic landscape of snoRNAs has not been characterized. Using the genotype and snoRNA expression data from The Cancer Genome Atlas, we characterized the ef...

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Autori principali: Yaoming Liu, Hang Ruan, Shengli Li, Youqiong Ye, Wei Hong, Jing Gong, Zhao Zhang, Ying Jing, Xiulan Zhang, Lixia Diao, Leng Han
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-06-01
Serie:Molecular Cancer
Soggetti:
Small nucleolar RNA
Genetic variants
Pharmacogenomics
Cancer
Accesso online:http://link.springer.com/article/10.1186/s12943-020-01228-z
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