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Improvement of Meloxicam Solubility Using a β-Cyclodextrin Complex Prepared via the Kneading Method and Incorporated into an Orally Disintegrating Tablet

Purpose: The aim of this research was to formulate and develop an orally disintegrating tablet (ODT) that incorporated a MEL/β-CD complex, using a quality by design (QbD) approach to enhance solubility and drug release. Methods: Multiple regression linear analysis was conducted to develop the knead...

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Main Authors: Ahmad Ainurofiq, Syaiful Choiri, Muhamad Ali Azhari, Chaterin Romauli Siagian, Bambang Budi Suryadi, Fea Prihapsara, Sholichah Rohmani
Format: Artigo
Language:Inglês
Published: Tabriz University of Medical Sciences 2016-09-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Meloxicam
β-cyclodextrin
Kneading
Orally disintegrating tablet
Quality by design
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-399.pdf
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