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Growth of the Developing Cerebral Cortex Is Controlled by MicroRNA-7 through the p53 Pathway

Proper growth of the mammalian cerebral cortex is crucial for normal brain functions and is controlled by precise gene-expression regulation. Here, we show that microRNA-7 (miR-7) is highly expressed in cortical neural progenitors and describe miR-7 sponge transgenic mice in which miR-7-silencing ac...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Andrew Pollock, Shan Bian, Chao Zhang, Zhengming Chen, Tao Sun
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2014-05-01
Rangatū:Cell Reports
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211124714002903
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