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Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs

We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non-inhaled anesthetics ketamine/xylazine. Intravenous...

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Autori principali: Yoshinobu Nagasawa, Kaori Sakai, Rui Kurimoto, Satoshi Kawakami, Megumi Aimoto, Akira Takahara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020-05-01
Serie:Journal of Pharmacological Sciences
Accesso online:http://www.sciencedirect.com/science/article/pii/S1347861320300177
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