Probiotic supplementation to mitigate berotralstat gastrointestinal side effects: a multicenter case series from the ITACA network

IntroductionBerotralstat, the first oral plasma kallikrein inhibitor approved for hereditary angioedema (HAE) prophylaxis, may be associated with gastrointestinal (GI) side effects, particularly during the first three months of therapy. Probiotics have been shown to reduce GI disturbances in several...

Descripció completa

Dades bibliogràfiques

Autors principals:	Antonio Gidaro, Maria Domenica Guarino, Francesco Arcoleo, Donatella Bignardi, Cristian D’Antonio, Luisa Brussino, Pietro Accardo, Stefania Nicola, Stefano Pucci, Miriam Cognigni, Valentina Popescu Janu, Chiara Cogliati, Emanuele Bizzi, Mauro Cancian
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	berotralstat gastrointestinal side effects hereditary angioedema ITACA long term prophylaxis microbiome
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1790199/full
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!