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Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae.

Correct repair of DNA double-strand breaks (DSBs) is critical for maintaining genome stability. Whereas gene conversion (GC)-mediated repair is mostly error-free, repair by break-induced replication (BIR) is associated with non-reciprocal translocations and loss of heterozygosity. We have previously...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Suvi Jain, Neal Sugawara, James E Haber
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-04-01
Schriftenreihe:PLoS Genetics
Online-Zugang:http://europepmc.org/articles/PMC4830573?pdf=render
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