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Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes

Type 2 diabetes mellitus (T2DM) increases the risk of cognitive decline and dementia. Disruptions in the cytochrome P450-soluble epoxide hydrolase (CYP450-sEH) pathway have been reported in T2DM, obesity and cognitive impairment. We examine linoleic acid (LA)-derived CYP450-sEH oxylipins and cogniti...

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Principais autores: Natasha Z. Anita, Felicia Kwan, Si Won Ryoo, Chelsi Major-Orfao, William Z. Lin, Shiropa Noor, Krista L. Lanctôt, Nathan Herrmann, Paul I. Oh, Baiju R. Shah, Jeremy Gilbert, Angela Assal, Ilana J. Halperin, Ameer Y. Taha, Walter Swardfager
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-07-01
coleção:Journal of Lipid Research
Assuntos:
Alzheimer’s disease
inflammation
lipids
obesity
oxidized lipids
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0022227523000688
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