Synthesis and evaluation of a novel vancomycin-infused, biomimetic bone graft using a rat model of spinal implant-associated infection

Background: Postoperative infection is a complication of spinal fusion surgery resulting in increased patient morbidity. Strategies including intraoperative application of powdered vancomycin have been proposed to reduce the incidence of infection; however, such antimicrobial effects are short-lived...

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Bibliografiske detaljer

Principais autores:	Christian J. Rajkovic, Jovanna A. Tracz, Trevor DeMordaunt, A. Daniel Davidar, Alexander Perdomo-Pantoja, Brendan F. Judy, Kevin Yang Zhang, Vaughn N. Hernandez, Jessica Lin, Julianna L. Lazzari, Ethan Cottrill, Timothy F. Witham
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2024-06-01
Serier:	North American Spine Society Journal
Fag:	Animal model Antibiotic-infused graft Bone graft Implant-associated infection Osteomyelitis Spinal fusion
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2666548424000167
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