Protective Effects of Kirenol against Lipopolysaccharide-Induced Acute Lung Injury through the Modulation of the Proinflammatory NFκB Pathway and the AMPK2-/Nrf2-Mediated HO-1/AOE Pathway

Acute lung injury (ALI) is an acute and life-threatening inflammatory disease of the lung parenchyma that is associated with high mortality worldwide. No therapeutic strategies have been developed for the mitigation of the proinflammatory response that characterizes ALI. Kirenol has anti-inflammator...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Frank Cheau-Feng Lin, Shiuan-Shinn Lee, Yi-Ching Li, Yung-Chuan Ho, Wen-Ying Chen, Chun-Jung Chen, Min-Wei Lee, Kun-Lin Yeh, Stella Chin-Shaw Tsai, Yu-Hsiang Kuan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-01-01
Schriftenreihe:	Antioxidants
Schlagworte:	lipopolysaccharide acute lung injury kirenol NF-κB pathway AMPK2/Nrf2-mediated HO-1 AOE pathway
Online-Zugang:	https://www.mdpi.com/2076-3921/10/2/204
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