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Mosaic quadrivalent influenza vaccine single nanoparticle characterization

Abstract Recent work by our laboratory and others indicates that co-display of multiple antigens on protein-based nanoparticles may be key to induce cross-reactive antibodies that provide broad protection against disease. To reach the ultimate goal of a universal vaccine for seasonal influenza, a mo...

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Principais autores: Rong Sylvie Yang, Maria Traver, Nathan Barefoot, Tyler Stephens, Casper Alabanza, Javier Manzella-Lapeira, Guozhang Zou, Jeremy Wolff, Yile Li, Melissa Resto, William Shadrick, Yanhong Yang, Vera B. Ivleva, Yaroslav Tsybovsky, Kevin Carlton, Joseph Brzostowski, Jason G. Gall, Q. Paula Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-02-01
coleção:Scientific Reports
Assuntos:
Fluorescence imaging
TIRFM
Fluorescent labeling
Size-exclusion chromatography
ELISA
Mass spectrometry
Acesso em linha:https://doi.org/10.1038/s41598-024-54876-2
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