Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn

<p>Abstract</p> <p>Background</p> <p>Sodium channel Nav1.7 has emerged as a target of considerable interest in pain research, since loss-of-function mutations in <it>SCN9A</it>, the gene that encodes Nav1.7, are associated with a syndrome of congenital insensitivity to pain, gain-of-function mutatio...

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Autors principals:	Black Joel A, Frézel Noémie, Dib-Hajj Sulayman D, Waxman Stephen G
Format:	Artigo
Idioma:	Inglês
Publicat:	SAGE Publishing 2012-11-01
Col·lecció:	Molecular Pain
Matèries:	Dorsal root ganglia Dorsal horn Intraepidermal nerve fiber Pain pathway Sodium channel Spinal cord
Accés en línia:	http://www.molecularpain.com/content/8/1/82
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