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MPS1 promotes timely spindle bipolarization to prevent kinetochore-microtubule attachment errors in oocytes

Abstract Incorrect kinetochore–microtubule attachment leads to chromosome segregation errors. The risk of incorrect attachment is high in acentrosomal oocytes, where kinetochores are surrounded by randomly oriented microtubules until spindle bipolarization. Regulation of the temporal relationship be...

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Auteurs principaux: Shuhei Yoshida, Reiko Nakagawa, Kohei Asai, Tomoya S Kitajima
Format: Artigo
Langue:Inglês
Publié: Springer Nature 2025-06-01
Collection:The EMBO Journal
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Accès en ligne:https://doi.org/10.1038/s44318-025-00461-w
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