Viral Evasion of Innate Immune Defense: The Case of Resistance of Pandemic H1N1 Influenza A Virus to Human Mannose-Binding Proteins

Mannose-binding lectins effectively inhibit most seasonal strains of influenza A virus and contribute to the innate host defense vs. these viruses. In contrast, pandemic IAV strains are largely resistant to these lectins, likely contributing to increased spread and worse outcomes. In this paper, we...

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Autori principali:	Mitchell R. White, Nikolaos M. Nikolaidis, Francis McCormack, Erika C. Crouch, Kevan L. Hartshorn
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-12-01
Serie:	Frontiers in Microbiology
Soggetti:	influenza Surfactant protein (SP-D) mannose binding lectin (MBL) cyanovirin hemagglutin
Accesso online:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.774711/full
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