A Natural Small Molecule Mitigates Kidney Fibrosis by Targeting Cdc42‐mediated GSK‐3β/β‐catenin Signaling

Abstract Kidney fibrosis is a common fate of chronic kidney diseases (CKDs), eventually leading to renal dysfunction. Yet, no effective treatment for this pathological process has been achieved. During the bioassay‐guided chemical investigation of the medicinal plant Wikstroemia chamaedaphne, a daph...

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Detalhes bibliográficos

Principais autores:	Xinrong Hu, Lu Gan, Ziwen Tang, Ruoni Lin, Zhou Liang, Feng Li, Changjian Zhu, Xu Han, Ruilin Zheng, Jiani Shen, Jing Yu, Ning Luo, Wenxing Peng, Jiaqing Tan, Xiaoyan Li, Jinjin Fan, Qiong Wen, Xin Wang, Jianbo Li, Xunhua Zheng, Qinghua Liu, Jianping Guo, Guo‐Ping Shi, Haiping Mao, Wei Chen, Sheng Yin, Yi Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-04-01
coleção:	Advanced Science
Assuntos:	Cdc42 GSK‐3β/β‐catenin kidney fibrosis natural small molecules
Acesso em linha:	https://doi.org/10.1002/advs.202307850
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