VCP regulates early tau seed amplification via specific cofactors
Abstract Background Neurodegenerative tauopathies may progress based on seeding by pathological tau assemblies, whereby an aggregate is released from one cell, gains entry to an adjacent or connected cell, and serves as a specific template for its own replication in the cytoplasm. Seeding into the c...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2025-01-01
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| Serie: | Molecular Neurodegeneration |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13024-024-00783-z |
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