Amino acid 17 in QRDR of Gyrase A plays a key role in fluoroquinolones susceptibility in mycobacteria

ABSTRACT The polymorphism at amino acid 17 of quinolone resistance-determining region of GyrA has been stated with a potential role in fluoroquinolone susceptibility in different mycobacterial species. However, no study has provided dependable evidence so far. Here, we verified that gene-edited Myco...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Shuai Wang, Jingran Zhang, H. M. Adnan Hameed, Jie Ding, Ping Guan, Xiange Fang, Jiacong Peng, Biyi Su, Shangming Ma, Yaoju Tan, Gregory M. Cook, Guoliang Zhang, Yongping Lin, Nanshan Zhong, Jinxing Hu, Jianxiong Liu, Tianyu Zhang
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	American Society for Microbiology 2023-12-01
سلاسل:	Microbiology Spectrum
الموضوعات:	fluoroquinolone mycobacteria intrinsic resistance gene editing Mycobacterium abscessus
الوصول للمادة أونلاين:	https://journals.asm.org/doi/10.1128/spectrum.02809-23
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!