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Interferon Regulatory Factor 9 Structure and Regulation

Interferon regulatory factor 9 (IRF9) is an integral transcription factor in mediating the type I interferon antiviral response, as part of the interferon-stimulated gene factor 3. However, the role of IRF9 in many important non-communicable diseases has just begun to emerge. The duality of IRF9’s r...

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Principais autores: Alvin Paul, Thean Hock Tang, Siew Kit Ng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-08-01
Serier:Frontiers in Immunology
Fag:
interferon regulatory factor 9
JAK-STAT
type I interferons
innate immunity
interferon-stimulated genes
antiviral defense
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2018.01831/full
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