Intravitreal injection of Huperzine A promotes retinal ganglion cells survival and axonal regeneration after optic nerve crush

Traumatic optic neuropathy (TON) is a condition that causes massive loss of retinal ganglion cells (RGCs) and their axonal fibers, leading to visual insufficiency. Several intrinsic and external factors can limit the regenerative ability of RGC after TON, subsequently resulting in RGC death. Hence,...

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Главные авторы:	Lai-Yang Zhou, Di Chen, Xin-Ran Guo, Yu-Qian Niu, Yong-Sai Xu, Dong-Fu Feng, Tie-Chen Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-05-01
Серии:	Frontiers in Cellular Neuroscience
Предметы:	traumatic optic neuropathy (TON) Huperzine A (HupA) retinal ganglion cell (RGC) axonal regeneration survival mTOR
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1145574/full
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