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Lidocaine inhibits the lung cancer progression through decreasing the HIST1H2BL levels via SIRT5 mediated succinylation

Abstract Lung cancer is a malignant tumor originating from the bronchial mucosa or gland of the lung. Recently, lidocaine, a widely used amide local anesthetic, was demonstrated to inhibit many cancer progression. This research was performed to explore the specific mechanism of lidocaine in the lung...

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Autori principali: Xuan Chen, Zhenbin Li, Xiangjun Yi, Cangyuan Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2024-10-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-024-73966-9
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