Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

Glycogen Synthase Kinase 3 (GSK3) has conserved functions across species but its role in the kidney is unclear. Here, the authors show that in the kidney podocyte cell of mice and related nephrocyte in Drosophila that GSK3 is a master regulator of function both during development and in maturity.

Dades bibliogràfiques

Autors principals:	J. A. Hurcombe, P. Hartley, A. C. Lay, L. Ni, J. J. Bedford, J. P. Leader, S. Singh, A. Murphy, C. L. Scudamore, E. Marquez, A. F. Barrington, V. Pinto, M. Marchetti, L.-F. Wong, J. Uney, M. A. Saleem, P. W. Mathieson, S. Patel, R. J. Walker, J. R. Woodgett, S. E. Quaggin, G. I. Welsh, R. J. M. Coward
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2019-01-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-018-08235-1
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