Vitamin A deficiency attenuates cardiac rupture in Stra6-deficient hearts following ischemic injury

BackgroundStimulated by retinoic acid gene 6 (STRA6) is a cell surface receptor that regulates cellular uptake of vitamin A metabolites and cardiac development. We hypothesized that Stra6 expression attenuates ischemic injury-induced heart failure following myocardial infarction (MI) by vitamin A-de...

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Egile Nagusiak:	Yannick Smolenski, Natali Froese, Paolo Galuppo, Christopher Werlein, Anna Gigina, Steven R. Talbot, Sergej Erschow, Dirk Wedekind, Robert Geffers, Norbert B. Ghyselinck, Heike Bähre, Jan C. Kamp, Lavinia Neubert, Melanie Ricke-Hoch, Johann Bauersachs, Christian Riehle
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2025-09-01
Saila:	Frontiers in Cardiovascular Medicine
Gaiak:	myocardial infarction heart failure cardiac remodeling wnt signaling vitamin A stimulated by retinoic acid gene 6
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1626769/full
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