Associations of childhood trauma with clinical features and inflammatory cytokines in adolescents with first-episode and recurrent major depressive disorder

BackgroundChildhood trauma is a significant risk factor for adolescents with major depressive disorder (MDD), but its associations with clinical features and inflammatory cytokines remain unclear across illness stages. This study aimed to investigate these associations by comparing adolescents with...

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Auteurs principaux:	Xi Zhang, Lewei Liu, Ruitong Li, Yun Zhang, Haojie Fan, Mingru Hao, Feng Geng, Daming Mo, Lei Xia, Huanzhong Liu
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-03-01
Collection:	Frontiers in Immunology
Sujets:	adolescent alexithymia childhood trauma depressive disorder inflammatory cytokines suicidal ideation
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1787595/full
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