Exploring phage–host interactions in Burkholderia cepacia complex bacterium to reveal host factors and phage resistance genes using CRISPRi functional genomics and transcriptomics

ABSTRACT Complex interactions of bacteriophages with their bacterial hosts determine phage host range and infectivity. While phage defense systems and host factors have been identified in model bacteria, they remain challenging to predict in non-model bacteria. In this paper, we integrate functional...

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Hlavní autoři:	Ben Diaz, Rohan Krishna, Joseph S. Schoeniger, Catherine M. Mageeney
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-11-01
Edice:	Microbiology Spectrum
Témata:	Burkholderia phage–host interaction bacteriophage
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.01936-25
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