Deuterium metabolic imaging phenotypes mouse glioblastoma heterogeneity through glucose turnover kinetics

Glioblastomas are aggressive brain tumors with dismal prognosis. One of the main bottlenecks for developing more effective therapies for glioblastoma stems from their histologic and molecular heterogeneity, leading to distinct tumor microenvironments and disease phenotypes. Effectively characterizin...

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Hlavní autoři:	Rui Vasco Simoes, Rafael Neto Henriques, Jonas L Olesen, Beatriz M Cardoso, Francisca F Fernandes, Mariana AV Monteiro, Sune N Jespersen, Tânia Carvalho, Noam Shemesh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2025-03-01
Edice:	eLife
Témata:	deuterium metabolic imaging glioblastoma glycolysis kinetic modeling mitochondrial metabolism
On-line přístup:	https://elifesciences.org/articles/100570
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