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In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Abstract Oligoclonal mixtures of broadly-neutralizing antibodies can neutralize complex compositions of similar and dissimilar antigens, making them versatile tools for the treatment of e.g., infectious diseases and animal envenomations. However, these biotherapeutics are complicated to develop due...

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Principais autores: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón, Andreas Hougaard Laustsen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2024-05-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-48539-z
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